Ceftizoxime is an antibiotic used to treat various diseases caused by bacterial infections, such as gonorrhea and urinary tract infections. This medicine can only be used with a doctor's prescription.

Ceftizoxime belongs to the third generation cephalosporin class of antibiotics which is available in injection form. Ceftizoxime works by binding and blocking the action of enzymes that play a role in the formation of bacterial cell walls. That way, the bacteria cannot grow and eventually die.

Trademarks of ceftizoxime: Cefim , Ceftien , Ceftizoxime Sodium, Tizos

What is Ceftizoxime

class Prescription drug
Category Cephalosporin antibiotics
Benefit Treating bacterial infections
Used by Adults and children
Ceftizoxime for pregnant and lactating women Category B: Animal studies have not demonstrated a risk to the fetus, but there are no controlled studies in pregnant women.

Ceftizoxime can be absorbed into breast milk. If you are breastfeeding, do not use this medicine without consulting your doctor first.

Form Inject

Warning Before Using Ceftizoxime

There are several things you need to pay attention to before using ceftizoxime, namely:

  • Do not use ceftizoxime if you have a history of allergies to this drug. Also tell your doctor if you have a history of allergies to penicillins or other cephalosporins.
  • Tell your doctor if you have or currently have liver disease, kidney disease , malnutrition, bronchial asthma , or digestive disorders, especially colitis .
  • Do not get vaccinated with live bacterial vaccines, such as typhoid vaccine or cholera vaccine, while being treated with ceftizoxime.
  • Tell your doctor if you are taking certain drugs, supplements or herbal medicines, to anticipate drug interactions.
  • Tell your doctor if you are pregnant, breastfeeding or planning a pregnancy.
  • Immediately consult a doctor if an allergic drug reaction or overdose occurs after using ceftizoxime.

Dosage and Rules for Use of Ceftizoxime

Ceftizoxime is given by injection into a muscle (intramuscular/IM) or into a vein (intravenous/IV). The following is the general dose of ceftizoxime based on the patient's condition:

Condition : Gonorrhea

  • Adult a: 1 gram single dose given by IM injection.

Condition: Urinary tract infection

  • Adult : 0.5 g per 12 hours given by IM injection or IV injection.

Condition : Other bacterial infections, such as bronchitis, cholangitis , bacterial endocarditis, cholecystitis , pneumonia, prostatitis, peritonitis , or sepsis.

  • Adult : 0.5–2 g daily, divided into 2–4 separate doses by IM injection or IV injection. For severe infections, the dose may be increased to 4 g per day.
  • Children ≥6 months : 40–80 mg/kg daily, divided into 2–4 divided doses. For severe infections, the dose may be increased to 120 mg/kg per day.

How to use Ceftizoxime correctly

Ceftizoxime can only be used with a doctor's prescription. Ceftizoxime injection will be given by a doctor or medical officer under the supervision of a doctor. This drug is used by injection into a muscle or vein.

The duration of using ceftizoxime will be adjusted to the patient's condition. The doctor will provide a schedule for injecting this drug. Follow the rules and schedule given by the doctor.

Ceftizoxime Interactions with Other Drugs

Ceftizoxime can cause drug interactions when used together with other drugs. Drug interactions that can occur are:

  • Increased risk of side effects when used with probenecid
  • Decreased effectiveness of live bacterial vaccines
  • Increased risk of kidney damage when used with aminoglycoside drugs

Ceftizoxime Side Effects and Dangers

Some of the side effects that can occur after using ceftizoxime are:

  • Pain at the injection area
  • Itchy skin rash
  • Stomach ache
  • Nauseous
  • Vomit
  • Numbness or tingling
  • Headache
  • Vaginal discharge or itching

Check with your doctor if the complaint doesn't go away or gets worse. Immediately see a doctor if you experience an allergic drug reaction or experience more serious side effects, such as:

  • bloody diarrhea
  • Irregular heartbeat
  • Fever , chills, aches or joint pain
  • Unusual fatigue
  • Easy bruising or bleeding
  • seizures
  • Weak muscles
  • Jaundice
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